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Structure of 16927-00-7
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2-(2-Chloroethyl)pyridine features a pyridine ring linked to a chloroethyl side chain, enabling efficient alkylation under mild conditions. This bifunctional scaffold integrates readily into synthetic routes requiring nucleophilic displacement or cyclization. The chlorine atom provides high reactivity for conjugate addition or transition-metal-catalyzed coupling, while the aromatic nitrogen stabilizes adjacent charge development. Ideal for building complex heterocycles and bioactive molecules in medicinal chemistry workflows.
2-(2-Chloroethyl)pyridine serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient construction of nitrogen-containing heterocycles. The chloroethyl side chain facilitates nucleophilic substitution reactions with amines, thiols, and other soft nucleophiles, while the pyridine ring provides a stable, electron-deficient scaffold for further functionalization. Its bench-stable nature and compatibility with standard coupling protocols make it ideal for synthesizing targeted bioactive molecules and macrocyclic frameworks.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 1760
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314
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Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P330-P363-P405-P501
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Lot numbers can be found on the outside label of a product: