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CS-W001157 4
Total: USD 88.00

Pyridin-3-ylboronic acid

  • CAS No. 1692-25-7

  • Cat. No. CS-D0809
  • Purity≥95%
  • MDL No.MFCD00674177

*For research and further manufacturing use only, not for direct human use.

Pyridin-3-ylboronic acid|CS-D0809

Structure of 1692-25-7

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General Information

  • CAS No. 1692-25-7
  • Cat. No. CS-D0809
  • Purity ≥95%
  • MDL No. MFCD00674177
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₆BNO₂
  • Molecular Weight 122.92
  • Synonym(s) None
  • SMILES OB(O)C1=CN=CC=C1

Description

3-Pyridinylboronic acid can be used as a reagent for:Phosphine-free Suzuki-Miyaura cross-coupling reactions. Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation. N-arylation using copper acetylacetonate catalyst. Copper-mediated cyanation and regioselective cyanation of electron-rich benzenes. It can also be used to prepare:New linear poly(phenylpyridyl) chains by Suzuki coupling. Oligopyridyl foldamers as mimics of a-helix twist. Many highly significant therapeutic enzymatic and kinase inhibitors and receptor antagonists.Pyridine substituted pyridinium N-(2-azinyl)aminides by reacting with dibromo pyridinium aminides via Suzuki coupling reaction.

Synthesis

  • Route1

    References

    • Matondo, Hubert; Souirti, Souad; Baboulene, Michel Synthetic Communications, 2003 , vol. 33, # 5 p. 795 - 800
  • Route2
    • In-stock
      3-Bromopyridine|CS-0008362
      626-55-1
    • null|null
      5419-55-6
    • ~75%
    • In-stock
      Pyridin-3-ylboronic acid|CS-D0809
      1692-25-7

    References

    • HUMAN BIOMOLECULAR RESEARCH INSTITUTE Patent: WO2005/66162 A1, 2005 ; Location in patent: Page/Page column 92 ; WO 2005/066162 A1
  • Route3
    • In-stock
      3-Bromopyridine|CS-0008362
      626-55-1
    • null|null
      121-43-7
    • ~%
    • In-stock
      Pyridin-3-ylboronic acid|CS-D0809
      1692-25-7

    References

    • US5981550 A1, ; US 5981550 A

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   -1.2386
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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