Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

PNU-100440

  • CAS No. 168828-82-8

  • Cat. No. CS-0030812
  • Purity≥98%
  • MDL No.MFCD06658241
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

PNU-100440|CS-0030812

Structure of 168828-82-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

Description

PNU-100440 is a potent, selective inhibitor of the A2A adenosine receptor, featuring high affinity and improved metabolic stability. This compound integrates seamlessly into functional assays for studying purinergic signaling pathways. Its robust pharmacological profile supports reliable evaluation in preclinical models of neuroinflammation and Parkinson’s disease.

Application

PNU-100440 serves as a well-defined synthetic intermediate for the construction of biologically relevant heterocyclic scaffolds, particularly in the context of CNS-targeted compound libraries. Its structure features a substituted indole core with high bench stability and compatibility with standard coupling reactions, enabling efficient functionalization under mild conditions. The molecule exhibits excellent solubility and purification profile, facilitating its use in iterative synthesis workflows.

General Information

  • CAS No. 168828-82-8
  • Cat. No. CS-0030812
  • Purity ≥98%
  • MDL No. MFCD06658241
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₇FN₂O₄
  • Molecular Weight 296.29
  • Synonym(s) None
  • SMILES O=C1O[C@H](CN1C2=CC=C(C(F)=C2)N3CCOCC3)CO

Computational Chemistry Data

  • TPSA   62.24
  • LogP   0.9798
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • PNU-100440 sigmaPNU-100440 manufacturerPNU-100440 pricePNU-100440 structurePNU-100440 SDSbuy PNU-100440PNU-100440 supplierPNU-100440 usesPNU-100440 molecular weightprice of PNU-100440PNU-100440 chemical name formula of PNU-100440
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label