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*For research and further manufacturing use only, not for direct human use.
Structure of 168828-82-8
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PNU-100440 is a potent, selective inhibitor of the A2A adenosine receptor, featuring high affinity and improved metabolic stability. This compound integrates seamlessly into functional assays for studying purinergic signaling pathways. Its robust pharmacological profile supports reliable evaluation in preclinical models of neuroinflammation and Parkinson’s disease.
PNU-100440 serves as a well-defined synthetic intermediate for the construction of biologically relevant heterocyclic scaffolds, particularly in the context of CNS-targeted compound libraries. Its structure features a substituted indole core with high bench stability and compatibility with standard coupling reactions, enabling efficient functionalization under mild conditions. The molecule exhibits excellent solubility and purification profile, facilitating its use in iterative synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: