4-Methylpiperazine-1-sulfonyl chloride

Name: 4-Methylpiperazine-1-sulfonyl chloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1688-95-5
Cat. No. CS-0447815
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-Methylpiperazine-1-sulfonyl chloride|CS-0447815

Structure of 1688-95-5

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1688-95-5
Cat. No. CS-0447815
Purity ≥98%
MDL No. None
Storage 4°C, sealed storage, away from moisture and light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₁₁ClN₂O₂S
Molecular Weight 198.67
Synonym(s) 4-Methyl-piperazin-1-ylsulphonyl chloride
SMILES CN1CCN(CC1)S(=O)(=O)Cl

Description

4-Methylpiperazine-1-sulfonyl chloride features a reactive sulfonyl chloride group appended to a methylated piperazine core, enabling efficient incorporation into pharmaceutical intermediates. The electron-rich heterocycle enhances solubility and stability under standard conditions, facilitating straightforward derivatization in synthetic workflows.

Application

4-Methylpiperazine-1-sulfonyl chloride serves as a versatile acylating agent for amine functionalization, enabling the efficient introduction of sulfonamide groups under mild conditions. Its bench-stable nature and high reactivity facilitate rapid synthesis of sulfonamide-containing building blocks, commonly employed in medicinal chemistry and API development. The methylated piperazine core provides enhanced solubility and metabolic stability, while the sulfonyl chloride moiety offers excellent functional group tolerance and straightforward purification via acid-base extraction.

Synthesis

Route1
- In-stock
  
  109-01-3
- ~44%
- In-stock
  
  1688-95-5
References
- Abbott Laboratories Patent: US5338726 A1, 1994 ; US 5338726 A

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 40.62
LogP -0.2826
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Piperazine compounds

Key Words

4-Methylpiperazine-1-sulfonyl chloride sigma4-Methylpiperazine-1-sulfonyl chloride manufacturer4-Methylpiperazine-1-sulfonyl chloride price4-Methylpiperazine-1-sulfonyl chloride structure4-Methylpiperazine-1-sulfonyl chloride SDSbuy 4-Methylpiperazine-1-sulfonyl chloride4-Methylpiperazine-1-sulfonyl chloride supplier4-Methylpiperazine-1-sulfonyl chloride uses4-Methylpiperazine-1-sulfonyl chloride molecular weightprice of 4-Methylpiperazine-1-sulfonyl chloride4-Methylpiperazine-1-sulfonyl chloride chemical name formula of 4-Methylpiperazine-1-sulfonyl chloride

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

4-Methylpiperazine-1-sulfonyl chloride

CAS No. 1688-95-5

Recommended Products