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Structure of 1678-68-8
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trans-Ethyl 4-aminocyclohexanecarboxylate features a rigid, conformationally stable cyclohexane core with a trans-configured amine and ester group. This stereochemical precision enhances its utility as a chiral building block in medicinal chemistry, enabling direct incorporation into bioactive scaffolds without epimerization risk under standard conditions.
trans-Ethyl 4-aminocyclohexanecarboxylate serves as a versatile chiral building block for medicinal chemistry and asymmetric synthesis. Its stable trans-configuration enables predictable stereochemical outcomes in downstream transformations. The pendant amine and ester functionalities offer orthogonal reactivity, facilitating derivatization via amidation, alkylation, or reduction. Bench-stable and readily purified by column chromatography, it functions efficiently in coupling reactions and heterocycle formation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: