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CS-W001157 4
Total: USD 88.00

2-Amino-5-bromo-6-methylpyridine

  • CAS No. 42753-71-9

  • Cat. No. CS-W007550
  • Purity≥97%
  • MDL No.MFCD00068230

*For research and further manufacturing use only, not for direct human use.

2-Amino-5-bromo-6-methylpyridine|CS-W007550

Structure of 42753-71-9

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General Information

  • CAS No. 42753-71-9
  • Cat. No. CS-W007550
  • Purity ≥97%
  • MDL No. MFCD00068230
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇BrN₂
  • Molecular Weight 187.04
  • Synonym(s) 6-Amino-3-bromo-2-picoline
  • SMILES CC1=C(Br)C=CC(N)=N1

Description

Aspartame is a synthetic and low-calorie sweetener and is used as an active ingredient in consumer foods, beverages, soft drinks, breath mints, sugar free chewing gum, cocoa mixes, frozen desserts, chewable vitamin supplements, milk drinks, cerals, pharmaceutical drugs and supplements, tabletop sweeteners and diet sodas.

Application

2-Amino-5-bromo-6-methylpyridine serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its bromine substituent. The amino and methyl groups provide orthogonal reactivity for further functionalization, while the pyridine core offers structural rigidity and tunable basicity. Bench-stable and readily purified by recrystallization, it facilitates efficient access to substituted heterocyclic scaffolds common in API development.

Synthesis

  • Route1

    References

    • ANORMED INC. Patent: WO2007/22371 A2, 2007 ; Location in patent: Page/Page column 49-50 ; WO 2007/022371 A2
  • Route2

    References

    • Yutilov; Svertilova; Minkina; Kirillova; Smolyar Russian Journal of Applied Chemistry, 2005 , vol. 78, # 5 p. 787 - 790
  • Route3

    References

    • Dunn, A. D.; Currie, A.; Hayes, L. E. Journal fuer Praktische Chemie (Leipzig), 1989 , vol. 331, # 3 p. 369 - 374

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   1.73472
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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