Lot numbers can be found on the outside label of a product:
3-Bromo-1-naphthoic acid
-
CAS No. 16726-66-2
- Cat. No. CS-0139704
- Purity≥97%
- MDL No.None
*For research and further manufacturing use only, not for direct human use.
Structure of 16726-66-2
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 16726-66-2
- Cat. No. CS-0139704
- Purity ≥97%
- MDL No. None
- Storage 4°C, protect from light
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₁H₇BrO₂
- Molecular Weight 251.08
- Synonym(s) 3-bromonaphthalene-1-carboxylic Acid
- SMILES O=C(O)C1=C2C=CC=CC2=CC(Br)=C1
Description
3-Bromo-1-naphthoic acid features a bromine substituent at the 3-position of the naphthalene core, enhancing electrophilic reactivity and enabling direct functionalization in cross-coupling processes. The carboxylic acid group provides a handle for derivatization via esterification, amidation, or salt formation. This bench-stable compound serves as a key intermediate in the synthesis of bioactive naphthyl derivatives and functional materials.
Application
3-Bromo-1-naphthoic acid serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the naphthalene ring and facilitating subsequent cross-coupling reactions. Its bromine substituent provides high reactivity in palladium-catalyzed transformations, while the carboxylic acid group offers orthogonal functionality for derivatization. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it ideal for iterative synthesis of complex heterocycles and pharmaceutical intermediates.
Synthesis
-
Route1
-
In-stock
![5-Bromobenzo[de]isochromene-1,3-dione|CS-W012311](https://file.chemscene.com/productPIC/CS-W012311.gif)
24050-49-5 - ~58%
-
In-stock
16726-66-2
References
-
PRESIDENT AND FELLOWS OF HARVARD COLLEGE; CHOREV, Michael; AKTAS, Bertal Huseyin; HALPERIN, Jose A.; WAGNER, Gerhard Patent: WO2012/6068 A2, 2012 ; Location in patent: Page/Page column 70-71 ;
-
-
Route2
-
In-stock
24050-49-5
- ~24%
-
In-stock
16726-66-2
-
51934-38-4
References
-
TAKEDA GMBH; HOFFMEYER, Angelika; BOER, Rainer; HEßMANN, Manuela; PAHL, Andreas; DUNKERN, Torsten; HARTUNG, Simone; ZITT, Christof; VOLZ, Jürgen; PRÄCHTER, Christiane; MAKHIJA, Mahindra; JAIN, Hiteshkumar; GAVADE, Sandip; PRABHU, Arati; TIWARI, Manojkumar; KECHE, Ashish; PATEL, Sarvesh Patent: WO2013/164326 A1, 2013 ; Location in patent: Page/Page column 19; 20 ;
-
-
Route3
-
6314-27-8 - ~%
-
In-stock
16726-66-2
References
-
WO2011/159067 A2, ; Page/Page column 54 ; WO 2011/159067 A2
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 37.3
- LogP 3.3005
- H_Acceptors 1
- H_Donors 1
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 3-Bromo-1-naphthoic acid sigma3-Bromo-1-naphthoic acid manufacturer3-Bromo-1-naphthoic acid price3-Bromo-1-naphthoic acid structure3-Bromo-1-naphthoic acid SDSbuy 3-Bromo-1-naphthoic acid3-Bromo-1-naphthoic acid supplier3-Bromo-1-naphthoic acid uses3-Bromo-1-naphthoic acid molecular weightprice of 3-Bromo-1-naphthoic acid3-Bromo-1-naphthoic acid chemical name formula of 3-Bromo-1-naphthoic acid