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CS-W001157 4
Total: USD 88.00

6-Bromo-2-chloroquinazolin-4-ol

  • CAS No. 167158-70-5

  • Cat. No. CS-0447747
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Bromo-2-chloroquinazolin-4-ol|CS-0447747

Structure of 167158-70-5

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General Information

  • CAS No. 167158-70-5
  • Cat. No. CS-0447747
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₄BrClN₂O
  • Molecular Weight 259.49
  • Synonym(s) 6-Bromo-2-chloroquinazolin-4(3H)-one
  • SMILES C1=CC2=NC(=NC(=C2C=C1Br)O)Cl

Synthesis

  • Route1

    References

    • GLAXOSMITHKLINE LLC; BANKA, Anna, Lindsey; BOTYANSZKI, Janos; DUAN, Maosheng; LEIVERS, Martin, Robert; SHOTWELL, John, Bradford; TALLANT, Matthew, David; DICKERSON, Scott, Howard; TAI, Vincent, W.-F.; MCFADYEN, Robert, Blount; REDMAN, Aniko, Maria; YU, Jianjun; LI, Xiofei; GARRIDO, Dulce, Maria; CATALANO, John, George; ADJABENG, George Patent: WO2012/87938 A1, 2012 ; Location in patent: Page/Page column 114 ; WO 2012/087938 A1
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 50, # 10 p. 2297 - 2300
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 50, # 10 p. 2297 - 2300

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   46.01
  • LogP   2.7513
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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