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CS-W001157 4
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(R)-(+)-1,1-Bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine

  • CAS No. 166764-19-8

  • Cat. No. CS-0106254
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(R)-(+)-1,1-Bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine|CS-0106254

Structure of 166764-19-8

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General Information

  • CAS No. 166764-19-8
  • Cat. No. CS-0106254
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₂₆N₂O₂
  • Molecular Weight 314.42
  • Synonym(s) (2R)-(-)-1,1-Bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine
  • SMILES CC(C)[C@@H](N)C(C1=CC=C(OC)C=C1)(N)C2=CC=C(OC)C=C2

Description

This chiral diamine features two methoxy-substituted aryl groups flanking a stereogenic center, delivering enhanced solubility and stability in polar solvents. The para-methoxy substituents contribute electron-donating character, while the methylated backbone improves steric definition for asymmetric synthesis applications.

Application

(R)-(+)-1,1-Bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine serves as a chiral diamine scaffold for asymmetric catalysis and ligand design. Its sterically defined backbone and ortho-methoxyaryl groups enable robust coordination to transition metals, facilitating enantioselective transformations. The compound exhibits excellent bench stability and ease of purification, making it suitable for scalable synthesis of catalysts used in hydrogenation and C–C bond formation.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H315-H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   70.5
  • LogP   2.8894
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   6

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