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CS-W001157 4
Total: USD 88.00

4-Cumylphenol

  • CAS No. 599-64-4

  • Cat. No. CS-W014998
  • Purity≥98%
  • MDL No.MFCD00002365

*For research and further manufacturing use only, not for direct human use.

4-Cumylphenol|CS-W014998

Structure of 599-64-4

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General Information

  • CAS No. 599-64-4
  • Cat. No. CS-W014998
  • Purity ≥98%
  • MDL No. MFCD00002365
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₅H₁₆O
  • Molecular Weight 212.29
  • Synonym(s) None
  • SMILES CC(C1=CC=CC=C1)(C2=CC=C(O)C=C2)C

Description

4-Cumylphenol features a phenolic hydroxyl group flanked by a para-substituted cumyl moiety, delivering enhanced steric and electronic stabilization. This structure imparts excellent bench stability and resistance to oxidative degradation, making it ideal for use in polymer additives and antioxidant formulations where long-term performance is critical.

Application

4-Cumylphenol serves as a versatile building block in organic synthesis, enabling the construction of functionalized aromatic scaffolds through standard coupling reactions. Its phenolic hydroxyl group offers reliable derivatization potential, while the bulky cumyl substituent imparts steric protection and enhanced stability under routine reaction conditions. The molecule functions effectively in pharmaceutical and agrochemical intermediates, demonstrating excellent compatibility with diverse functional groups and facilitating purification via crystallization or chromatography.

Synthesis

  • Route1

    References

    • Pan, Yijun; Holmes, Christopher P. Organic Letters, 2001 , vol. 3, # 17 p. 2769 - 2770
  • Route2
    • null|null
      98-83-9
    • null|null
      108-95-2
    • ~86%
    • In-stock
      4-Cumylphenol|CS-W014998
      599-64-4
    • In-stock
      2,4-Bis(2-phenylpropan-2-yl)phenol|CS-W009417
      2772-45-4

    References

    • Journal of the American Chemical Society, , vol. 131, # 29 p. 9914 - 9915
  • Route3
    • null|null
      98-83-9
    • null|null
      108-95-2
    • ~82%
    • In-stock
      4-Cumylphenol|CS-W014998
      599-64-4

    References

    • Niggemann, Meike; Bisek, Nicola Chemistry - A European Journal, 2010 , vol. 16, # 37 p. 11246 - 11249

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   3.7181
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

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