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Structure of 166525-49-1
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1-(4,6-Dichloro-3-pyridyl)propan-1-one features a pyridyl core bearing two chlorine substituents at the 4- and 6-positions, providing enhanced electron-withdrawing character. The acetyl side chain offers a reactive carbonyl for nucleophilic addition, enabling direct incorporation into heterocyclic frameworks. This structure supports efficient conjugation in synthetic intermediates requiring halogenated aromatic handles.
1-(4,6-Dichloro-3-pyridyl)propan-1-one serves as a versatile building block in medicinal chemistry, enabling the construction of pyridine-containing scaffolds via nucleophilic addition and condensation reactions. Its dichloropyridyl core provides enhanced electrophilicity at the C4 and C6 positions, facilitating functionalization in late-stage diversification. The ketone functionality offers direct access to α-alkylated or β-amino derivatives under mild conditions. Bench-stable and compatible with standard purification methods, it functions reliably in multistep syntheses targeting bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: