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CS-W001157 4
Total: USD 88.00

Thiophene-2-sulfonyl chloride

  • CAS No. 16629-19-9

  • Cat. No. CS-W017078
  • Purity≥97%
  • MDL No.MFCD00005426

*For research and further manufacturing use only, not for direct human use.

Thiophene-2-sulfonyl chloride|CS-W017078

Structure of 16629-19-9

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General Information

  • CAS No. 16629-19-9
  • Cat. No. CS-W017078
  • Purity ≥97%
  • MDL No. MFCD00005426
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₃ClO₂S₂
  • Molecular Weight 182.64
  • Synonym(s) 2-Thiophenesulfonylchloride; Thiophene-2-sulfonyl chloride
  • SMILES O=S(C1=CC=CS1)(Cl)=O

Description

Bromo-PEG5-azide contain a bromide group and a terminal azide. The bromide (Br) is a very good leaving group for nucleophilic reactions. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG5 spacer increases solubility in aqueous media.

Synthesis

  • Route1
    • null|null
      188290-36-0
    • ~90%
    • In-stock
      Thiophene-2-sulfonyl chloride|CS-W017078
      16629-19-9

    References

    • Cremlyn, Richard J.; Goulding, Kenneth H.; Swinbourne, Frederick J.; Yung, Kin-Man Phosphorus and Sulfur and the Related Elements, 1981 , vol. 10, p. 111 - 120
  • Route2
    • Thiophene-2-sulfonic acid|CS-0096224
      79-84-5
    • ~%
    • In-stock
      Thiophene-2-sulfonyl chloride|CS-W017078
      16629-19-9

    References

    • Journal of Organic Chemistry, , vol. 73, # 10 p. 3967 - 3969
  • Route3
    • In-stock
      2-Iodothiophene|CS-W007589
      3437-95-4
    • ~7%
    • In-stock
      Thiophene-2-sulfonyl chloride|CS-W017078
      16629-19-9
    • 5-Iodothiophene-2-sulfonyl chloride|CS-0259773
      55854-47-2

    References

    • Bulletin of the Chemical Society of Japan, , vol. 58, # 3 p. 1063 - 1064

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   34.14
  • LogP   1.6756
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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