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CS-W001157 4
Total: USD 88.00

Fmoc-NH-PEG1-C2-acid

  • CAS No. 1654740-73-4

  • Cat. No. CS-0114328
  • Purity≥98%
  • MDL No.MFCD16294357

*For research and further manufacturing use only, not for direct human use.

Fmoc-NH-PEG1-C2-acid|CS-0114328

Structure of 1654740-73-4

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General Information

  • CAS No. 1654740-73-4
  • Cat. No. CS-0114328
  • Purity ≥98%
  • MDL No. MFCD16294357
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₁NO₅
  • Molecular Weight 355.38
  • Synonym(s) None
  • SMILES O=C(O)CCOCCNC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O

Description

Fmoc-NH-PEG1-C2-acid features a C2 spacer linking the Fmoc-protected amine to a terminal carboxylic acid, enabling modular conjugation in peptide synthesis. The PEG1 unit imparts solubility and flexibility, while the acid group facilitates coupling reactions under standard conditions. This derivative supports efficient immobilization and functionalization in bioconjugate applications.

Application

Fmoc-NH-PEG1-C2-acid serves as a versatile bifunctional linker for peptide and biomolecule conjugation. The Fmoc group enables efficient solid-phase synthesis, while the PEG1 spacer provides solubility and reduced aggregation. The terminal carboxylic acid facilitates amide coupling with amines, enabling site-specific conjugation in therapeutic development and chemical biology applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   3.0164
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   8

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