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CS-W001157 4
Total: USD 88.00

3-(4-Iodophenyl)propanoic acid

  • CAS No. 1643-29-4

  • Cat. No. CS-0157511
  • Purity≥98%
  • MDL No.MFCD00017597

*For research and further manufacturing use only, not for direct human use.

3-(4-Iodophenyl)propanoic acid|CS-0157511

Structure of 1643-29-4

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General Information

  • CAS No. 1643-29-4
  • Cat. No. CS-0157511
  • Purity ≥98%
  • MDL No. MFCD00017597
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉IO₂
  • Molecular Weight 276.07
  • Synonym(s) None
  • SMILES O=C(O)CCC1=CC=C(I)C=C1

Description

3-(4-Iodophenyl)propanoic acid features a para-iodinated phenyl group linked to a propionic acid chain, enabling direct incorporation into Suzuki-Miyaura cross-coupling reactions. This bench-stable, moisture-tolerant reagent facilitates efficient synthesis of biaryl scaffolds in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • Hydrocinnamic acid, 99%|CS-1269054
      501-52-0
    • ~74%
    • In-stock
      3-(4-Iodophenyl)propanoic acid|CS-0157511
      1643-29-4

    References

    • SYDDANSK UNIVERSITET; ULVEN, Trond; CHRISTIANSEN, Elisabeth Patent: WO2010/12650 A1, 2010 ; Location in patent: Page/Page column 38 ; WO 2010/012650 A1
  • Route2

    References

    • Christiansen, Elisabeth; Urban, Christian; Merten, Nicole; Liebscher, Kathrin; Karlsen, Kasper K.; Hamacher, Alexandra; Spinrath, Andreas; Bond, Andrew D.; Drewke, Christel; Ullrich, Susanne; Kassack, Matthias U.; Kostenis, Evi; Ulven, Trond Journal of Medicinal Chemistry, 2008 , vol. 51, # 22 p. 7061 - 7064
  • Route3
    • null|null
      25100-55-4
    • ~%
    • In-stock
      3-(4-Iodophenyl)propanoic acid|CS-0157511
      1643-29-4

    References

    • Journal of the American Chemical Society, , vol. 64, p. 1436,1438

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.3084
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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