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Structure of 164149-27-3
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tert-Butyl 4-(3-bromopropyl)piperidine-1-carboxylate features a bromoalkyl chain appended to a piperidine nitrogen, enabling direct functionalization in synthetic sequences. The tert-butyl carbamate group provides stability and ease of deprotection under mild acidic conditions. This reagent facilitates the construction of complex amine-containing architectures in medicinal chemistry and materials science.
tert-Butyl 4-(3-bromopropyl)piperidine-1-carboxylate serves as a versatile bifunctional building block for medicinal chemistry and process development. The piperidine nitrogen is protected as a stable tert-butyl carbamate, while the terminal bromide enables efficient SN2 reactions, including coupling with nucleophiles, palladium-catalyzed cross-couplings, or incorporation into heterocyclic scaffolds. Its bench-stable nature and ease of purification make it ideal for multi-step synthesis workflows requiring selective functionalization.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: