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CS-W001157 4
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tert-Butyl 4-(3-bromopropyl)piperidine-1-carboxylate

  • CAS No. 164149-27-3

  • Cat. No. CS-0187677
  • Purity≥97%
  • MDL No.MFCD23701754
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-(3-bromopropyl)piperidine-1-carboxylate|CS-0187677

Structure of 164149-27-3

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Description

tert-Butyl 4-(3-bromopropyl)piperidine-1-carboxylate features a bromoalkyl chain appended to a piperidine nitrogen, enabling direct functionalization in synthetic sequences. The tert-butyl carbamate group provides stability and ease of deprotection under mild acidic conditions. This reagent facilitates the construction of complex amine-containing architectures in medicinal chemistry and materials science.

Application

tert-Butyl 4-(3-bromopropyl)piperidine-1-carboxylate serves as a versatile bifunctional building block for medicinal chemistry and process development. The piperidine nitrogen is protected as a stable tert-butyl carbamate, while the terminal bromide enables efficient SN2 reactions, including coupling with nucleophiles, palladium-catalyzed cross-couplings, or incorporation into heterocyclic scaffolds. Its bench-stable nature and ease of purification make it ideal for multi-step synthesis workflows requiring selective functionalization.

General Information

  • CAS No. 164149-27-3
  • Cat. No. CS-0187677
  • Purity ≥97%
  • MDL No. MFCD23701754
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₂₄BrNO₂
  • Molecular Weight 306.24
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)N1CCC(CC1)CCCBr

Computational Chemistry Data

  • TPSA   29.54
  • LogP   3.8086
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   3

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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