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CS-W001157 4
Total: USD 88.00

4-(1H-Pyrazol-4-yl)morpholine

  • CAS No. 1638764-62-1

  • Cat. No. CS-0528594
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(1H-Pyrazol-4-yl)morpholine|CS-0528594

Structure of 1638764-62-1

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General Information

  • CAS No. 1638764-62-1
  • Cat. No. CS-0528594
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₁N₃O
  • Molecular Weight 153.18
  • Synonym(s) None
  • SMILES N1(C2=CNN=C2)CCOCC1

Description

4-(1H-Pyrazol-4-yl)morpholine features a pyrazole ring fused to a morpholine moiety, delivering enhanced solubility and metabolic stability. This scaffold integrates readily into medicinal chemistry libraries, offering favorable pharmacokinetic properties for target engagement in kinase and GPCR pathways.

Application

4-(1H-Pyrazol-4-yl)morpholine serves as a versatile building block in medicinal chemistry, enabling rapid access to bioactive heterocyclic scaffolds. Its morpholine ring provides favorable solubility and metabolic stability, while the pyrazole moiety offers robust hydrogen-bonding capacity and structural rigidity. The compound exhibits excellent bench stability and compatibility with standard coupling reactions, facilitating efficient derivatization for target-focused library synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   41.15
  • LogP   0.2463
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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