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tert-Butyl N-{4-aminobicyclo[2.2.1]heptan-1-yl}carbamate

  • CAS No. 1630907-27-5

  • Cat. No. CS-0047901
  • Purity≥98%
  • MDL No.MFCD27987309

*For research and further manufacturing use only, not for direct human use.

tert-Butyl N-{4-aminobicyclo[2.2.1]heptan-1-yl}carbamate|CS-0047901

Structure of 1630907-27-5

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General Information

  • CAS No. 1630907-27-5
  • Cat. No. CS-0047901
  • Purity ≥98%
  • MDL No. MFCD27987309
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₂N₂O₂
  • Molecular Weight 226.32
  • Synonym(s) tert-Butyl (4-aminobicyclo[2.2.1]heptan-1-yl)carbamate
  • SMILES N[C@@]12CC[C@](C2)(NC(OC(C)(C)C)=O)CC1

Description

tert-Butyl N-{4-aminobicyclo[2.2.1]heptan-1-yl}carbamate features a rigid, bicyclic scaffold that imparts conformational stability to the pendant amine. The tert-butyl carbamate group provides protection under standard conditions while enabling selective deprotection in acidic environments. This combination supports efficient integration into complex molecular architectures, particularly in medicinal chemistry and asymmetric synthesis workflows.

Application

tert-Butyl N-{4-aminobicyclo[2.2.1]heptan-1-yl}carbamate serves as a versatile, bench-stable building block for the synthesis of constrained bicyclic scaffolds. The protected amine enables selective functionalization and facilitates incorporation into medicinal chemistry libraries. Its stability under standard reaction conditions and ease of deprotection make it ideal for iterative synthesis workflows requiring precise control over nitrogen reactivity.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   1.9251
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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