Fmoc-Trp(N-CH2-COOtBu)-OH

Name: Fmoc-Trp(N-CH2-COOtBu)-OH
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CAS No. 1629658-33-8
Cat. No. CS-0439250
Molecule weight540.61
Purity≥97%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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General Information

CAS No. 1629658-33-8
Cat. No. CS-0439250
Purity ≥97%
MDL No. None
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃₂H₃₂N₂O₆
Molecular Weight 540.61
Synonym(s) N-Fmoc-1-(2-tert-butoxy-2-oxoethyl)-L-tryptophan
SMILES C(OC(N[C@@H](CC=1C=2C(N(CC(OC(C)(C)C)=O)C1)=CC=CC2)C(O)=O)=O)C3C=4C(C=5C3=CC=CC5)=CC=CC4

Description

Fmoc-Trp(N-CH2-COOtBu)-OH features a uniquely protected indole nitrogen, enabling selective conjugation in peptide synthesis. The tBu ester group offers enhanced stability and compatibility with standard deprotection protocols. This derivative supports efficient incorporation of tryptophan into challenging sequences where side-chain reactivity must be minimized.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

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Computational Chemistry Data

TPSA 106.86
LogP 5.5174
H_Acceptors 6
H_Donors 2
Rotatable_Bonds 8

Other Classifications

Building Blocks Functional Group Fmoc

Building Blocks Skeleton Aromatic heterocycle compounds Indole compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Tryptophan and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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Fmoc-Trp(N-CH2-COOtBu)-OH

CAS No. 1629658-33-8

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