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Structure of 1627924-19-9
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This pyrazole aldehyde features a tetrahydro-2H-pyran-2-yl protected alcohol and an iodinated aromatic ring, enabling selective late-stage functionalization. The boronate ester moiety integrates readily into cross-coupling reactions under standard conditions, while the aldehyde group offers direct access to hydrazone derivatives for probe development.
3-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazole-4-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its iodide and aldehyde functionalities. The tetrahydro-2H-pyran-2-yl group provides orthogonal protection for the pyrazole nitrogen, enhancing stability and facilitating selective deprotection. Its well-defined reactivity profile supports efficient synthesis of complex heterocyclic scaffolds under standard bench conditions.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: