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CS-W001157 4
Total: USD 88.00

4-Methoxymethoxyphenylboronic acid

  • CAS No. 162662-27-3

  • Cat. No. CS-0030290
  • Purity≥98%
  • MDL No.MFCD03412067

*For research and further manufacturing use only, not for direct human use.

4-Methoxymethoxyphenylboronic acid|CS-0030290

Structure of 162662-27-3

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General Information

  • CAS No. 162662-27-3
  • Cat. No. CS-0030290
  • Purity ≥98%
  • MDL No. MFCD03412067
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BO₄
  • Molecular Weight 181.98
  • Synonym(s) 4-(Methoxymethoxy)phenylboronic acid
  • SMILES COCOC1=CC=C(B(O)O)C=C1

Description

4-Methoxymethoxyphenylboronic acid features a boronate moiety appended to a phenyl ring bearing a methoxymethoxy substituent at the para position. This configuration enhances solubility and stability under standard conditions while enabling efficient coupling in Suzuki-Miyaura reactions. The protecting group is readily removable, facilitating downstream functionalization.

Synthesis

  • Route1

    References

    • Hart, Matthew E.; Suchland, Katherine L.; Miyakawa, Motonori; Bunzow, James R.; Grandy, David K.; Scanlan, Thomas S. Journal of Medicinal Chemistry, 2006 , vol. 49, # 3 p. 1101 - 1112
  • Route2
    • 1-Iodo-4-(methoxymethoxy)benzene|CS-1140773
      98491-29-3
    • ~85%
    • In-stock
      4-Methoxymethoxyphenylboronic acid|CS-0030290
      162662-27-3

    References

    • Selepe, Mamoalosi A.; Drewes, Siegfried E.; Van Heerden, Fanie R. Journal of Natural Products, 2010 , vol. 73, # 10 p. 1680 - 1685
  • Route3
    • null|null
      106-41-2
    • ~%
    • In-stock
      4-Methoxymethoxyphenylboronic acid|CS-0030290
      162662-27-3

    References

    • Journal of Medicinal Chemistry, , vol. 49, # 3 p. 1101 - 1112

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   58.92
  • LogP   -0.6509
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

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