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CS-W001157 4
Total: USD 88.00

(2-(Methoxymethoxy)phenyl)boronic acid

  • CAS No. 115377-93-0

  • Cat. No. CS-0134705
  • Purity≥98%
  • MDL No.MFCD10566597
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(2-(Methoxymethoxy)phenyl)boronic acid|CS-0134705

Structure of 115377-93-0

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Description

This boronate moiety integrates a methoxymethoxy-protected phenyl group, enabling stable handling and selective deprotection in late-stage functionalization. The ortho-substituted arylboronic acid facilitates efficient cross-coupling under standard conditions, delivering complex biaryl architectures with high chemoselectivity and minimal protodeboronation.

Application

(2-(Methoxymethoxy)phenyl)boronic acid serves as a versatile boron-containing building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl architectures. The methoxymethoxy group provides orthogonal protection for phenolic hydroxyls, enhancing stability and functional group tolerance during synthesis. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for iterative coupling strategies in medicinal chemistry and materials science.

General Information

  • CAS No. 115377-93-0
  • Cat. No. CS-0134705
  • Purity ≥98%
  • MDL No. MFCD10566597
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁BO₄
  • Molecular Weight 181.98
  • Synonym(s) 2-(Methoxymethoxy)phenylboronic acid
  • SMILES OB(O)C1=CC=CC=C1OCOC

Computational Chemistry Data

  • TPSA   58.92
  • LogP   -0.6509
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   4

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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