2-Chloro-1H-imidazole

Name: 2-Chloro-1H-imidazole
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 16265-04-6
Cat. No. CS-0020071
Purity≥97%
MDL No.MFCD02179530

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 16265-04-6

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 16265-04-6
Cat. No. CS-0020071
Purity ≥97%
MDL No. MFCD02179530
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₃H₃ClN₂
Molecular Weight 102.52
Synonym(s) 2-Chloroimidazole; oroimidazoL
SMILES ClC1=NC=CN1

Description

2-Chloro-1H-imidazole is a bench-stable, moisture-tolerant heterocycle featuring a chlorine substituent at the 2-position, enabling direct functionalization in cross-coupling and electrophilic substitution reactions. This electron-deficient imidazole serves as a robust scaffold for synthesizing bioactive molecules and advanced intermediates in medicinal chemistry and materials science.

Application

2-Chloro-1H-imidazole serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted imidazoles via nucleophilic displacement or transition-metal-catalyzed coupling. Its bench-stable nature and compatibility with diverse functional groups facilitate straightforward incorporation into complex molecular architectures. The chloride moiety provides a reliable handle for C–C and C–heteroatom bond formation, making it a practical reagent for medicinal chemistry and process development workflows.

Synthesis

Route1
- In-stock
  
  61278-81-7
- ~83%
- In-stock
  
  16265-04-6
References
- Otsuka Pharmaceutical Company, Limited Patent: EP1553088 A1, 2005 ; Location in patent: Page/Page column 52 ;
Route2
- 15469-97-3
- ~71%
- In-stock
  
  16265-04-6
References
- RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY Patent: US2011/282067 A1, 2011 ; Location in patent: Page/Page column 2-3 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS05,GHS07
Signal Word : Danger	UN#: 1759
Class : 8	Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 28.68
LogP 1.0631
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Key Words

2-Chloro-1H-imidazole sigma2-Chloro-1H-imidazole manufacturer2-Chloro-1H-imidazole price2-Chloro-1H-imidazole structure2-Chloro-1H-imidazole SDSbuy 2-Chloro-1H-imidazole2-Chloro-1H-imidazole supplier2-Chloro-1H-imidazole uses2-Chloro-1H-imidazole molecular weightprice of 2-Chloro-1H-imidazole2-Chloro-1H-imidazole chemical name formula of 2-Chloro-1H-imidazole

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

2-Chloro-1H-imidazole

CAS No. 16265-04-6

Recommended Products