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Structure of 1622844-16-9
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2-Fluoro-6-methylpyridin-4-amine features a strategically positioned fluorine atom and methyl group on the pyridine ring, delivering enhanced electron-withdrawing character and improved metabolic stability. This configuration enables efficient coupling in cross-coupling reactions and facilitates incorporation into bioactive scaffolds requiring moderate lipophilicity and targeted electronic tuning.
2-Fluoro-6-methylpyridin-4-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to pyridine-based scaffolds through palladium-catalyzed cross-coupling reactions. Its fluorine and amino groups provide orthogonal reactivity for late-stage functionalization, while the methyl group enhances metabolic stability and modulates electronic properties. The compound exhibits good bench stability and compatibility with standard purification methods, facilitating integration into multi-step synthetic sequences for API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: