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Structure of 1622840-18-9
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3-Bromo-1-cyclopropyl-1H-pyrazole is a bench-stable heterocyclic building block featuring a bromine atom at the 3-position and a cyclopropyl group attached to nitrogen. This configuration enables direct functionalization in cross-coupling reactions, offering efficient access to substituted pyrazole scaffolds with tailored steric and electronic profiles.
3-Bromo-1-cyclopropyl-1H-pyrazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-established reactivity at the bromine site. The cyclopropyl group enhances metabolic stability and modulates lipophilicity, while the pyrazole core provides hydrogen-bonding capability and structural rigidity. This compound exhibits excellent bench stability, facilitates straightforward purification, and functions reliably in standard coupling protocols for constructing complex heterocyclic scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H320-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: