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CS-W001157 4
Total: USD 88.00

2,6-Difluorophenylboronic acid

  • CAS No. 162101-25-9

  • Cat. No. CS-W009261
  • Purity≥97%
  • MDL No.MFCD00792436

*For research and further manufacturing use only, not for direct human use.

2,6-Difluorophenylboronic acid|CS-W009261

Structure of 162101-25-9

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General Information

  • CAS No. 162101-25-9
  • Cat. No. CS-W009261
  • Purity ≥97%
  • MDL No. MFCD00792436
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅BF₂O₂
  • Molecular Weight 157.91
  • Synonym(s) None
  • SMILES FC1=C(B(O)O)C(F)=CC=C1

Description

2,6-Difluorophenylboronic acid can be used:As a substrate in the model reaction of SuzukiMiyaura coupling with4-chloro-3-methylanisole.To prepare 4-bromo-2,3,5,6-tetrafluorobiphenyl, a key intermediate for the synthesis of 2,6-difluorinated oligophenyls applicable in organic semiconductors.To prepare ethyl 4-(2,6-difluorophenyl)nicotinate, a key intermediate for the synthesis of 4-phenyl pyridine based potent TGR5 agonists.

Synthesis

  • Route1

    References

    • Journal of Organometallic Chemistry, , vol. 598, # 1 p. 127 - 135
  • Route2
    • In-stock
      2-Bromo-1,3-difluorobenzene|CS-W007374
      64248-56-2
    • null|null
      121-43-7
    • ~25%
    • In-stock
      2,6-Difluorophenylboronic acid|CS-W009261
      162101-25-9

    References

    • Frohn; Adonin; Bardin; Starichenko Zeitschrift fur Anorganische und Allgemeine Chemie, 2002 , vol. 628, # 13 p. 2827 - 2833
  • Route3
    • null|null
      372-18-9
    • ~%
    • In-stock
      2,6-Difluorophenylboronic acid|CS-W009261
      162101-25-9

    References

    • Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, , vol. 373, p. 1 - 15

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   40.46
  • LogP   -0.3554
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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