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Structure of 162100-55-2
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5-(Trifluoromethyl)indoline features a trifluoromethyl group at the 5-position of the indoline scaffold, imparting enhanced electron-withdrawing character and metabolic stability. This bench-stable heterocycle integrates readily into pharmaceutical scaffolds, serving as a key building block for bioactive molecules in medicinal chemistry.
5-(Trifluoromethyl)indoline serves as a valuable building block in medicinal chemistry, offering enhanced metabolic stability and lipophilicity due to the electron-withdrawing trifluoromethyl group. Its indoline core facilitates integration into diverse heterocyclic scaffolds, while the pendant amine enables straightforward derivatization. The compound exhibits good bench stability and is compatible with standard coupling and functionalization protocols, making it a practical choice for synthesizing kinase inhibitors, CNS-targeted agents, and other bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: