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Tert-butyl 1,2,6-triazaspiro[2.5]oct-1-ene-6-carboxylate

  • CAS No. 1620483-21-7

  • Cat. No. CS-0144530
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Tert-butyl 1,2,6-triazaspiro[2.5]oct-1-ene-6-carboxylate|CS-0144530

Structure of 1620483-21-7

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General Information

  • CAS No. 1620483-21-7
  • Cat. No. CS-0144530
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₇N₃O₂
  • Molecular Weight 211.26
  • Synonym(s) None
  • SMILES O=C(N(CC1)CCC21N=N2)OC(C)(C)C

Description

Tert-butyl 1,2,6-triazaspiro[2.5]oct-1-ene-6-carboxylate features a rigid spirocyclic scaffold integrating a strained triazaspiro framework with a latent enamine functionality. This bench-stable, moisture-tolerant building block enables efficient access to complex nitrogen-rich heterocycles via controlled ring-opening or cycloaddition cascades.

Application

Tert-butyl 1,2,6-triazaspiro[2.5]oct-1-ene-6-carboxylate serves as a versatile spirocyclic building block for the synthesis of nitrogen-containing heterocycles. Its rigid bicyclic framework enables controlled stereochemistry in downstream transformations, while the tert-butyl ester provides stability and ease of purification. The molecule reacts predictably with nucleophiles and participates in cycloaddition reactions, facilitating access to complex scaffolds relevant to medicinal chemistry and catalytic process development.

Safety Information

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GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Danger
UN#: 1325
Class : 4.1
Packing Group : Ⅱ
Hazard Statements : H315-H319-H228
Precautionary Statements : P210-P240-P241-P264-P280-P302+P352-P305+P351+P338-P362+P364-P370+P378

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Computational Chemistry Data

  • TPSA   54.26
  • LogP   2.1794
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   0

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