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CS-W001157 4
Total: USD 88.00

2,5-Dichloropyridine

  • CAS No. 16110-09-1

  • Cat. No. CS-W016342
  • Purity≥97%
  • MDL No.MFCD00006239

*For research and further manufacturing use only, not for direct human use.

2,5-Dichloropyridine|CS-W016342

Structure of 16110-09-1

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General Information

  • CAS No. 16110-09-1
  • Cat. No. CS-W016342
  • Purity ≥97%
  • MDL No. MFCD00006239
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃Cl₂N
  • Molecular Weight 147.99
  • Synonym(s) 4-Aminophenylacetamide
  • SMILES C1=CC(=NC=C1Cl)Cl

Description

2,5-Dichloropyridine undergoes cross-coupling reaction with arylboronic acids in the presence of [1,4-bis-(diphenylphosphine)butane]palladium (II) dichloride as catalyst.2,5-Dichloropyridine was used in the synthesis of 6-halo-pyridin-3-yl boronic acids and esters.

Synthesis

  • Route1

    References

    • Verma, Sanny; Saran, Sandeep; Jain, Suman L. Applied Catalysis A: General, 2014 , vol. 472, p. 178 - 183
  • Route2

    References

    • US3947457 A1, ;
  • Route3

    References

    • Shiao, Min-Jen; Shyu, Li-Ming; Tarng, Kai-Yih; Ma, Ying-Tsun Synthetic Communications, 1990 , vol. 20, # 19 p. 2971 - 2977

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.89
  • LogP   2.3884
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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