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Structure of 1610028-25-5
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2-(3-Oxocyclobutyl)acetic acid features a strained cyclobutane ring fused to a ketone and carboxylic acid moiety, enabling unique reactivity in cycloaddition and functionalization workflows. The electron-deficient carbonyl enhances nucleophilic attack susceptibility, while the acetic acid side chain facilitates derivatization under standard conditions. This structure supports integration into bioactive scaffolds and synthetic intermediates requiring rigid, polarized frameworks.
2-(3-Oxocyclobutyl)acetic acid serves as a versatile building block for cyclobutane-containing scaffolds, enabling efficient access to biologically relevant heterocycles and medicinal chemistry intermediates. Its α-ketoacid functionality facilitates nucleophilic additions, decarboxylation pathways, and transition-metal-catalyzed couplings. The compound exhibits good bench stability and compatibility with common protecting group strategies, supporting its use in multi-step synthesis and scale-up applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: