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Structure of 16097-60-2
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2-Amino-4-chloro-6-(trifluoromethyl)pyrimidine features a trifluoromethyl group that enhances electron deficiency and metabolic stability, while the amino and chloro substituents enable selective coupling reactions. This pyrimidine scaffold serves as a key building block in medicinal chemistry, particularly for kinase inhibitors and antiviral agents.
2-Amino-4-chloro-6-(trifluoromethyl)pyrimidine serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds via nucleophilic substitution and cross-coupling reactions. Its trifluoromethyl group enhances metabolic stability and lipophilicity, while the amino and chloro functionalities provide orthogonal handles for sequential derivatization. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for scalable synthesis of kinase inhibitors and other bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: