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CS-W001157 4
Total: USD 88.00

2-(Thiazol-2-yl)propan-2-ol

  • CAS No. 16077-78-4

  • Cat. No. CS-0447679
  • Molecule weight143.21
  • Purity≥98%
  • MDL No.MFCD03211903

*For research and further manufacturing use only, not for direct human use.

2-(Thiazol-2-yl)propan-2-ol|CS-0447679

Structure of 16077-78-4

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General Information

  • CAS No. 16077-78-4
  • Cat. No. CS-0447679
  • Purity ≥98%
  • MDL No. MFCD03211903
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₉NOS
  • Molecular Weight 143.21
  • Synonym(s) alpha,alpha-Dimethyl-2-thiazolemethanol
  • SMILES CC(C)(C1=NC=CS1)O

Synthesis

  • Route1
    • null|null
      288-47-1
    • null|null
      67-64-1
    • ~%
    • 2-(Thiazol-2-yl)propan-2-ol|CS-0447679
      16077-78-4

    References

    • GILEAD CONNECTICUT, INC.; BLOMGREN, Peter, A.; CURRIE, Kevin, S.; HALCOMB, Randall; KROPF, Jeffrey, E.; LEE, Seung, H.; LI, Jiayao; LO, Jennifer, R.; MITCHELL, Scott, A.; SCHMITT, Aaron; WU, Qiaoyin; XIONG, Jin-min; XU, Jianjun; ZHAO, Zhongdong; CHANDRASEKHAR, Jayaraman; LANSDON, Eric Patent: WO2013/188856 A1, 2013 ; Location in patent: Paragraph 0467 ;
  • Route2
    • null|null
      288-47-1
    • ~%
    • 2-(Thiazol-2-yl)propan-2-ol|CS-0447679
      16077-78-4

    References

    • Merck Frosst Canada and Co. Patent: US6639077 B2, 2003 ;
  • Route3

    References

    • MERCK SHARP and DOHME CORP.; ALTMAN, Michael, D.; BIENSTOCK, Corey, E.; BUTCHER, John, W.; CHILDERS, Kaleen Konrad; DI FRANCESCO, Maria Emilia; DONOFRIO, Anthony; ELLIS, John Michael; FISCHER, Christian; HAIDLE, Andrew, M.; JEWELL, James, P.; KNOWLES, Sandra Lee; NORTHRUP, Alan, B.; OTTE, Ryan, D.; PETERSON, Scott, L.; SMITH, Graham Frank Patent: WO2013/52394 A1, 2013 ; Location in patent: Paragraph 00251 ;

Safety Information

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GHS Pictogram : N/A
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Signal Word : N/A
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.3705
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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