Z-Ala-Ala-OH

Name: Z-Ala-Ala-OH
Brand: ChemScene
Availability: InStock
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CAS No. 16012-70-7
Cat. No. CS-0133283
Purity≥98%
MDL No.MFCD00037234

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 16012-70-7

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Description

Z-Ala-Ala-OH is a dipeptide derivative featuring a benzyloxycarbonyl (Z) group at the N-terminus and a free hydroxyl terminus. This configuration enables selective coupling in peptide synthesis, offering enhanced stability during handling and compatibility with standard activation protocols. The protected N-terminus facilitates controlled chain elongation in solid-phase and solution-phase workflows.

Application

Z-Ala-Ala-OH serves as a well-established dipeptide building block for peptide synthesis, offering robust bench stability and compatibility with standard coupling protocols. The N-terminal benzyloxycarbonyl (Z) group provides effective protection against racemization during activation, while the C-terminal carboxylic acid enables direct coupling or derivatization. Its orthogonal functionality supports sequential assembly in multi-step peptide workflows, making it a reliable component in the synthesis of bioactive peptides and peptidomimetics.

General Information

CAS No. 16012-70-7
Cat. No. CS-0133283
Purity ≥98%
MDL No. MFCD00037234
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₄H₁₈N₂O₅
Molecular Weight 294.30
Synonym(s) None
SMILES C[C@@H](C(O)=O)NC([C@H](C)NC(OCC1=CC=CC=C1)=O)=O

Computational Chemistry Data

TPSA 104.73
LogP 0.8906
H_Acceptors 4
H_Donors 3
Rotatable_Bonds 6

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Alanine and derivatives

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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Z-Ala-Ala-OH

CAS No. 16012-70-7

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