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CS-W001157 4
Total: USD 88.00

[1,2,4]Triazolo[4,3-a]pyridin-7-amine hydrochloride

  • CAS No. 1598386-14-1

  • Cat. No. CS-0155552
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

[1,2,4]Triazolo[4,3-a]pyridin-7-amine hydrochloride|CS-0155552

Structure of 1598386-14-1

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Description

This triazolopyridine derivative features a hydrogen-bond-rich scaffold with enhanced solubility and stability under standard conditions. The hydrochloride salt form improves handling and crystallinity, enabling straightforward integration into medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.

Application

[1,2,4]Triazolo[4,3-a]pyridin-7-amine hydrochloride serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to nitrogen-rich scaffolds prevalent in kinase inhibitors and CNS-targeted therapeutics. Its amine functionality facilitates straightforward derivatization via amidation, alkylation, and Suzuki coupling, while the hydrochloride salt ensures excellent bench stability and solubility in polar solvents. The triazolopyridine core exhibits favorable functional group tolerance and orthogonal reactivity, making it a reliable component in multi-step synthesis workflows.

General Information

  • CAS No. 1598386-14-1
  • Cat. No. CS-0155552
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇ClN₄
  • Molecular Weight 170.60
  • Synonym(s) [1,2,4triazolo[4,3-apyridin-7-amine
  • SMILES NC1=CC2=NN=CN2C=C1.Cl

Computational Chemistry Data

  • TPSA   56.21
  • LogP   0.7333
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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