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CS-W001157 4
Total: USD 88.00

Dmt-2'-f-dc(ac) amidite

  • CAS No. 159414-99-0

  • Cat. No. CS-0149469
  • Molecule weight789.83
  • Purity≥95%
  • MDL No.MFCD12912404

*For research and further manufacturing use only, not for direct human use.

Dmt-2'-f-dc(ac) amidite|CS-0149469

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General Information

  • CAS No. 159414-99-0
  • Cat. No. CS-0149469
  • Purity ≥95%
  • MDL No. MFCD12912404
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₁H₄₉FN₅O₈P
  • Molecular Weight 789.83
  • Synonym(s) 2'-F-Ac-dC Phosphoramidite; DMT-2′Fluoro-dC(ac) Phosphoramidite
  • SMILES COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](F)[C@H](N5C(N=C(NC(C)=O)C=C5)=O)O4

Description

Dmt-2'-f-dc(ac) amidite delivers a protected, fluorescently tagged nucleoside building block for solid-phase oligonucleotide synthesis. The dimethoxytrityl (Dmt) group at the 5′-end enables efficient purification via UV monitoring, while the 2′-fluoro modification enhances nuclease resistance and binding affinity. This amidite incorporates seamlessly into DNA/RNA strands, enabling site-specific labeling and improved stability in therapeutic and diagnostic applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   146.4
  • LogP   7.12428
  • H_Acceptors   12
  • H_Donors   1
  • Rotatable_Bonds   18

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