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CS-W001157 4
Total: USD 88.00

5-Cyanoindole

  • CAS No. 15861-24-2

  • Cat. No. CS-M1444
  • Purity≥97%
  • MDL No.MFCD00005669

*For research and further manufacturing use only, not for direct human use.

5-Cyanoindole|CS-M1444

Structure of 15861-24-2

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General Information

  • CAS No. 15861-24-2
  • Cat. No. CS-M1444
  • Purity ≥97%
  • MDL No. MFCD00005669
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₆N₂
  • Molecular Weight 142.16
  • Synonym(s) None
  • SMILES N#CC1=CC=C2NC=CC2=C1

Description

Pomalidomide 4'-PEG5-acid contains a cereblon ligand and a hydrophilic PEG5 linker. This product is ready for conjugation to target proteins for PROTAC R&D.

Synthesis

  • Route1
    • In-stock
      5-Bromoindole|CS-D0617
      10075-50-0
    • null|null
      143-33-9
    • ~95%
    • In-stock
      5-Cyanoindole|CS-M1444
      15861-24-2

    References

    • Journal of the American Chemical Society, , vol. 125, # 10 p. 2890 - 2891
  • Route2
    • null|null
      773837-37-9
    • In-stock
      5-Iodo-1H-indole|CS-W004099
      16066-91-4
    • ~94%
    • In-stock
      5-Cyanoindole|CS-M1444
      15861-24-2

    References

    • WO2010/42998 A1, ; Page/Page column 51 ; WO 2010/042998 A1
  • Route3
    • In-stock
      5-Bromoindole|CS-D0617
      10075-50-0
    • null|null
      544-92-3
    • ~84%
    • In-stock
      5-Cyanoindole|CS-M1444
      15861-24-2

    References

    • WO2007/98418 A1, ; Page/Page column 96-97 ; WO 2007/098418 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.58
  • LogP   2.03958
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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