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CS-W001157 4
Total: USD 88.00

4-Aminonicotinonitrile

  • CAS No. 15827-84-6

  • Cat. No. CS-0133802
  • Purity≥95%
  • MDL No.MFCD04035595

*For research and further manufacturing use only, not for direct human use.

4-Aminonicotinonitrile|CS-0133802

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General Information

  • CAS No. 15827-84-6
  • Cat. No. CS-0133802
  • Purity ≥95%
  • MDL No. MFCD04035595
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅N₃
  • Molecular Weight 119.12
  • Synonym(s) 4-aminopyridine-3-carbonitrile
  • SMILES N#CC1=C(N)C=CN=C1

Description

4-Aminonicotinonitrile features a pyridine ring bearing both an amino group and a nitrile functionality at the 4-position, enabling dual reactivity in synthetic transformations. This electron-deficient heterocycle serves as a key building block for pharmaceutical intermediates and functional materials. The compound exhibits favorable solubility in polar solvents and stability under standard bench conditions.

Application

4-Aminonicotinonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyridine-based heterocycles and bioactive scaffolds. Its dual functionality—amine and nitrile groups—supports diverse transformations including amidation, cyclization, and nucleophilic addition. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis campaigns and API intermediate development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501

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Computational Chemistry Data

  • TPSA   62.7
  • LogP   0.53548
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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