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CS-W001157 4
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2-Methyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole dihydrochloride

  • CAS No. 157327-48-5

  • Cat. No. CS-0030233
  • Molecule weight196.08
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Methyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole dihydrochloride|CS-0030233

Structure of 157327-48-5

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General Information

  • CAS No. 157327-48-5
  • Cat. No. CS-0030233
  • Purity ≥95%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁Cl₂N₃
  • Molecular Weight 196.08
  • Synonym(s) 2-Methyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole hydrochloride
  • SMILES CN1N=C(CNC2)C2=C1.[H]Cl.[H]Cl

Description

This dihydrochloride salt features a rigid, electron-rich heterocyclic core with enhanced solubility and stability under standard conditions. The 2-methyl substitution provides steric shielding, while the protonated pyrazole nitrogen improves handling and reactivity in synthetic transformations. Designed for efficient integration into medicinal chemistry campaigns requiring robust, bench-stable scaffolds.

Application

2-Methyl-2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole dihydrochloride serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to nitrogen-rich scaffolds. Its stable dihydrochloride form enhances solubility and handling, while the tetrahydropyrrolopyrazole core exhibits favorable functional group tolerance and reactivity in standard coupling and derivatization protocols. This compound facilitates rapid exploration of bioactive analogs in target-directed synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   29.85
  • LogP   0.8669
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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