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CS-W001157 4
Total: USD 88.00

tert-Butyl piperidine-4-carboxylate hydrochloride

  • CAS No. 892493-65-1

  • Cat. No. CS-W003099
  • Purity≥97%
  • MDL No.MFCD03788468
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl piperidine-4-carboxylate hydrochloride|CS-W003099

Structure of 892493-65-1

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Description

tert-Butyl piperidine-4-carboxylate hydrochloride features a sterically hindered piperidine core with a bench-stable, moisture-tolerant tert-butyl ester handle. This protected amine derivative integrates readily into synthetic sequences requiring selective N-functionalization or late-stage derivatization. The hydrochloride salt enhances solubility in polar solvents while maintaining stability under standard handling conditions.

Application

tert-Butyl piperidine-4-carboxylate hydrochloride serves as a stable, bench-ready building block for medicinal chemistry and process development. Its tert-butyl ester functionality enables selective deprotection under mild acidic conditions, while the piperidine core provides a versatile scaffold for late-stage functionalization. The hydrochloride salt enhances solubility and crystallinity, facilitating purification and handling in standard synthetic workflows.

General Information

  • CAS No. 892493-65-1
  • Cat. No. CS-W003099
  • Purity ≥97%
  • MDL No. MFCD03788468
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀ClNO₂
  • Molecular Weight 221.72
  • Synonym(s) 4-Piperidinecarboxylicacid, 1,1-dimethylethyl ester
  • SMILES O=C(C1CCNCC1)OC(C)(C)C.Cl

Computational Chemistry Data

  • TPSA   38.33
  • LogP   1.7495
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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