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Structure of 15723-90-7
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4-Nitrobenzamidine hydrochloride features a para-nitro group that enhances electrophilic reactivity, enabling efficient coupling in amide bond formation. The amidine moiety provides strong basicity and stability under standard conditions, while the hydrochloride salt ensures excellent solubility and ease of handling in aqueous and polar organic media.
4-Nitrobenzamidine hydrochloride serves as a versatile building block for the synthesis of bioactive heterocycles and amidine-containing pharmaceutical intermediates. Its dual functionality—nitro group for reduction or electrophilic substitution and amidine moiety for salt formation and hydrogen bonding—enables straightforward derivatization in aqueous and polar organic media. The hydrochloride salt enhances bench stability, solubility, and ease of purification, making it well-suited for scalable medicinal chemistry campaigns and solid-phase synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: