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CS-W001157 4
Total: USD 88.00

3-Methoxybicyclo[1.1.1]pentane-1-carboxylic acid

  • CAS No. 156329-86-1

  • Cat. No. CS-0051291
  • Purity≥95%
  • MDL No.MFCD30489919

*For research and further manufacturing use only, not for direct human use.

3-Methoxybicyclo[1.1.1]pentane-1-carboxylic acid|CS-0051291

Structure of 156329-86-1

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General Information

  • CAS No. 156329-86-1
  • Cat. No. CS-0051291
  • Purity ≥95%
  • MDL No. MFCD30489919
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀O₃
  • Molecular Weight 142.15
  • Synonym(s) None
  • SMILES COC12CC(C2)(C(O)=O)C1

Description

This bicyclic scaffold delivers a rigid, sterically constrained core ideal for probing conformational effects in medicinal chemistry. The methoxy group enhances solubility and modulates electronic properties, while the carboxylic acid enables direct conjugation or derivatization. Designed for efficient integration into bioactive molecules under standard conditions.

Application

3-Methoxybicyclo[1.1.1]pentane-1-carboxylic acid serves as a rigid, sterically constrained building block for medicinal chemistry and materials science. Its bicyclic core imparts exceptional metabolic stability and modulates physicochemical properties, while the carboxylic acid functionality enables direct derivatization or coupling reactions. The methoxy group enhances solubility and offers a handle for further functionalization. This compound facilitates the synthesis of diverse heterocyclic scaffolds and bioactive molecules with improved pharmacokinetic profiles.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   0.6401
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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