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CS-W001157 4
Total: USD 88.00

3-Methylbicyclo[1.1.1]pentan-1-amine hydrochloride

  • CAS No. 796963-34-3

  • Cat. No. CS-0051247
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Methylbicyclo[1.1.1]pentan-1-amine hydrochloride|CS-0051247

Structure of 796963-34-3

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Description

3-Methylbicyclo[1.1.1]pentan-1-amine hydrochloride is a bench-stable, moisture-tolerant amine featuring a rigid bicyclic scaffold that imparts exceptional conformational restraint. This structure enhances metabolic stability and facilitates selective binding in bioactive molecule design. The hydrochloride salt form ensures excellent solubility and ease of handling in aqueous reaction media.

Application

3-Methylbicyclo[1.1.1]pentan-1-amine hydrochloride serves as a rigid, sterically constrained amine building block for medicinal chemistry and target-oriented synthesis. Its bicyclic scaffold imparts conformational stability and enhances metabolic resistance, while the protonated amine facilitates salt formation for improved solubility and handling. The compound enables efficient incorporation into diverse molecular architectures via standard amine coupling reactions, offering high functional group tolerance and compatibility with common synthetic workflows.

General Information

  • CAS No. 796963-34-3
  • Cat. No. CS-0051247
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClN
  • Molecular Weight 133.62
  • Synonym(s) 3-Methylbicyclo[1.1.1]pentan-1-aminehydrochloride
  • SMILES Cl.CC12CC(N)(C1)C2

Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.3095
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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