Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(Bromomethyl)-6-methoxypyridine

  • CAS No. 156094-63-2

  • Cat. No. CS-W006716
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(Bromomethyl)-6-methoxypyridine|CS-W006716

Structure of 156094-63-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 156094-63-2
  • Cat. No. CS-W006716
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈BrNO
  • Molecular Weight 202.05
  • Synonym(s) 6-Bromomethyl-2-methoxypyridine
  • SMILES COC1=CC=CC(CBr)=N1

Description

2-(Bromomethyl)-6-methoxypyridine features a reactive bromomethyl group flanked by a methoxy-substituted pyridine ring, enabling direct functionalization in cross-coupling and nucleophilic substitution reactions. This bench-stable, moisture-tolerant reagent integrates readily into synthetic sequences requiring selective alkylation or chain extension under mild conditions.

Application

2-(Bromomethyl)-6-methoxypyridine serves as a versatile synthetic building block for the installation of pyridylmethyl linkages in medicinal chemistry and catalysis research. The bromomethyl group enables efficient SN₂ functionalization, while the 6-methoxypyridine core provides a stable, electron-deficient heterocyclic scaffold compatible with palladium-catalyzed cross-coupling reactions. Its bench-stable nature and straightforward purification support reliable use in multi-step synthesis.

Synthesis

  • Route1

    References

    • AMGEN INC.; ASHTON, Kate; BARTBERGER, Michael David; BO, Yunxin; BRYAN, Marian C.; CROGHAN, Michael; FOTSCH, Christopher Harold; HALE, Clarence Henderson; KUNZ, Roxanne Kay; LIU, Longbin; NISHIMURA, Nobuko; NORMAN, Mark H.; PENNINGTON, Lewis Dale; POON, Steve Fong; STEC, Markian Myroslaw; ST. JEAN, David, Joseph, Jr.; TAMAYO, Nuria A.; TEGLEY, Christopher Michael; YANG, Kevin Chao Patent: WO2012/27261 A1, 2012 ; Location in patent: Page/Page column 577; 578 ; WO 2012/027261 A1
  • Route2

    References

    • Gray; Konopski; Langlois Synthetic Communications, 1994 , vol. 24, # 10 p. 1367 - 1379
  • Route3

    References

    • ARRAY BIOPHARMA INC.; BOYS, Mark Laurence; BRADLEY, Michael; DELISLE, Robert Kirk; HENNINGS, D. David; KENNEDY, April L.; MARMSATER, Fredrik P.; MEDINA, Matthew; MUNSON, Mark C.; RAST, Bryson; RIZZI, James P.; RODRIGUEZ, Martha E.; TOPALOV, George T.; ZHAO, Qian Patent: WO2011/79076 A1, 2011 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302+H312-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P302+P352-P304+P340-P330-P362+P364-P363-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   22.12
  • LogP   1.9851
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-(Bromomethyl)-6-methoxypyridine sigma2-(Bromomethyl)-6-methoxypyridine manufacturer2-(Bromomethyl)-6-methoxypyridine price2-(Bromomethyl)-6-methoxypyridine structure2-(Bromomethyl)-6-methoxypyridine SDSbuy 2-(Bromomethyl)-6-methoxypyridine2-(Bromomethyl)-6-methoxypyridine supplier2-(Bromomethyl)-6-methoxypyridine uses2-(Bromomethyl)-6-methoxypyridine molecular weightprice of 2-(Bromomethyl)-6-methoxypyridine2-(Bromomethyl)-6-methoxypyridine chemical name formula of 2-(Bromomethyl)-6-methoxypyridine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label