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Structure of 156001-68-2
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This methyl ester derivative features a cyano group at the meta position and a hydroxyl substituent at the para position relative to the carboxylic acid ester, enabling precise tuning of electronic properties and solubility. The ortho-ester functionality enhances reactivity in coupling reactions, while the phenolic hydroxyl supports hydrogen bonding and derivatization. Designed for synthetic applications requiring balanced polarity and stability under standard conditions.
3-Cyano-4-hydroxybenzoic acid methyl ester serves as a versatile building block for heterocyclic synthesis and medicinal chemistry campaigns. Its orthogonal functionality—cyano, phenolic hydroxyl, and ester groups—enables sequential transformations including cyclization, amidation, and nucleophilic addition. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for scale-up and multi-step synthetic sequences in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: