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Structure of 15573-67-8
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4-Hydroxyphenylglyoxylate features a phenolic hydroxyl group adjacent to a reactive glyoxylate moiety, enabling selective conjugation in bioconjugation workflows. This electron-deficient ketone derivative facilitates efficient coupling with nucleophiles under mild conditions, offering high stability and predictable reactivity for probe synthesis.
4-Hydroxyphenylglyoxylate serves as a versatile building block for ortho-quinone methide precursors and enables direct access to substituted phenolic scaffolds via decarboxylation or cycloaddition. Its hydroxyl and glyoxylate functionalities support orthogonal transformations, including esterification, amidation, and metal-catalyzed coupling reactions. The compound exhibits bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis in medicinal chemistry and natural product derivatization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: