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CS-W001157 4
Total: USD 88.00

1,3-Bis(2-hydroxyethyl)urea

  • CAS No. 15438-70-7

  • Cat. No. CS-0142124
  • Molecule weight148.16
  • Purity≥97%
  • MDL No.MFCD00522193

*For research and further manufacturing use only, not for direct human use.

1,3-Bis(2-hydroxyethyl)urea|CS-0142124

Structure of 15438-70-7

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General Information

  • CAS No. 15438-70-7
  • Cat. No. CS-0142124
  • Purity ≥97%
  • MDL No. MFCD00522193
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂N₂O₃
  • Molecular Weight 148.16
  • Synonym(s) Urea, 1,3-bis(2-hydroxyethyl)- (8ci)
  • SMILES O=C(NCCO)NCCO

Description

1,3-Bis(2-hydroxyethyl)urea features two hydroxyethyl substituents flanking a central urea core, delivering enhanced solubility and hydrogen-bonding capacity. This bifunctional scaffold integrates readily into polymer backbones and bioconjugation workflows, offering robust stability under standard conditions.

Application

1,3-Bis(2-hydroxyethyl)urea serves as a stable, water-soluble bifunctional building block featuring two primary hydroxyl groups and a central urea linkage. It facilitates the synthesis of polyether-urea copolymers and acts as a versatile scaffold in the construction of bioactive heterocycles. Its high functional group tolerance enables reliable coupling reactions under mild conditions, supporting efficient purification and scalability in process chemistry workflows.

Synthesis

  • Route1
    • In-stock
      Oxazolidin-2-one|CS-W007548
      497-25-6
    • null|null
      141-43-5
    • ~39%
    • In-stock
      1,3-Bis(2-hydroxyethyl)urea|CS-0142124
      15438-70-7

    References

    • L'OREAL Patent: US2006/39879 A1, 2006 ; Location in patent: Page/Page column 4 ;
  • Route2
    • null|null
      124-38-9
    • null|null
      141-43-5
    • ~0%
    • In-stock
      Oxazolidin-2-one|CS-W007548
      497-25-6
    • In-stock
      1,3-Bis(2-hydroxyethyl)urea|CS-0142124
      15438-70-7

    References

    • Kubota, Yasuhiko; Kodaka, Masato; Tomohiro, Takenori; Okuno, Hiroaki (Yohmei) Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 1 p. 5 - 6
  • Route3
    • S,S'-Dimethyldithiocarbonate|CS-0015824
      868-84-8
    • null|null
      141-43-5
    • ~54%
    • In-stock
      Oxazolidin-2-one|CS-W007548
      497-25-6
    • In-stock
      1,3-Bis(2-hydroxyethyl)urea|CS-0142124
      15438-70-7

    References

    • Leung, Man-Kit; Lai, Jun-Liang; Lau, King-Hang; Yu, Hsiao-Hua; Hsiao, Hsiang-Ju Journal of Organic Chemistry, 1996 , vol. 61, # 12 p. 4175 - 4179

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   81.59
  • LogP   -1.7298
  • H_Acceptors   3
  • H_Donors   4
  • Rotatable_Bonds   4

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