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Structure of 154257-85-9
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1-(3-Bromo-5-chlorophenyl)ethanone features a brominated and chlorinated aromatic ring fused to a ketone-bearing ethyl side chain. This electron-deficient aryl ketone integrates readily into cross-coupling reactions, offering stable intermediates under standard conditions. The dual halogenation enables selective functionalization in synthetic pathways requiring orthogonal reactivity.
1-(3-Bromo-5-chlorophenyl)ethanone serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling efficient construction of biaryl scaffolds via palladium-catalyzed cross-coupling reactions. The molecule’s bromo and chloro substituents provide orthogonal reactivity for sequential functionalization, while the ketone group facilitates nucleophilic addition and enolization. Bench-stable and compatible with standard purification methods, it functions reliably in multi-step syntheses requiring selective transformation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: