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Structure of 1537457-36-5
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2-(4-Chloro-2-fluorophenyl)propan-2-ol is a bench-stable, moisture-tolerant aryl alcohol featuring a sterically hindered tertiary carbon center. This structural motif enhances stability and facilitates selective functionalization in synthetic sequences. The para-chloro and ortho-fluoro substituents confer electron-withdrawing character, enabling precise tuning of reactivity in pharmaceutical intermediates and agrochemical scaffolds.
2-(4-Chloro-2-fluorophenyl)propan-2-ol serves as a key chiral building block in the synthesis of pharmaceutical intermediates, particularly for compounds targeting central nervous system disorders. Its tertiary alcohol functionality provides enhanced stability and facilitates efficient functionalization via oxidation or substitution reactions. The molecule exhibits favorable bench stability and compatibility with standard synthetic protocols, enabling straightforward incorporation into complex molecular architectures through well-established coupling and cyclization strategies.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: