3-Bromo-N,N-dimethylbenzenesulfonamide

Name: 3-Bromo-N,N-dimethylbenzenesulfonamide
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 153435-80-4
Cat. No. CS-0196818
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

3-Bromo-N,N-dimethylbenzenesulfonamide|CS-0196818

Structure of 153435-80-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 153435-80-4
Cat. No. CS-0196818
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀BrNO₂S
Molecular Weight 264.14
Synonym(s) 3-BROMO,N, N-DIMETHYLBENZENESULFONAMIDE
SMILES CN(C)S(=O)(=O)C1=CC=CC(=C1)Br

Description

3-Bromo-N,N-dimethylbenzenesulfonamide is a bench-stable sulfonamide featuring a bromine substituent at the meta position, enabling direct functionalization in cross-coupling reactions. The dimethylamino group enhances solubility and electronic modulation, while the sulfonamide scaffold provides robustness under standard reaction conditions. This compound serves as a key intermediate in medicinal chemistry and materials synthesis.

Application

3-Bromo-N,N-dimethylbenzenesulfonamide serves as a versatile building block in medicinal chemistry, enabling late-stage functionalization via palladium-catalyzed cross-coupling reactions. The bromo group exhibits high reactivity in Suzuki, Stille, and Negishi couplings, while the sulfonamide moiety provides polarity and hydrogen-bonding capacity. Its bench-stable crystalline form facilitates handling, purification, and integration into complex molecule synthesis.

Synthesis

Route1
- In-stock
  
  2905-24-0
- 124-40-3
- ~95%
- In-stock
  
  153435-80-4
References
- SGX PHARMACEUTICALS, INC. Patent: WO2006/15124 A2, 2006 ; Location in patent: Page/Page column 93 ; WO 2006/015124 A2
Route2
- In-stock
  
  2905-24-0
- 506-59-2
- ~90%
- In-stock
  
  153435-80-4
References
- Kyowa Hakko Kirin Co., Ltd. Patent: EP2090570 A1, 2009 ; Location in patent: Page/Page column 82 ; EP 2090570 A1
Route3
- In-stock
  
  153435-79-1
- In-stock
  
  4637-24-5
- ~94%
- In-stock
  
  153435-80-4
References
- Fairley, Gary; Hall, Catherine; Greenwood, Ryan Synlett, 2013 , vol. 24, # 5 art. no. ST-2013-D0004-L, p. 570 - 574

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P233-P260-P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 37.38
LogP 1.6994
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 2

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

3-Bromo-N,N-dimethylbenzenesulfonamide sigma3-Bromo-N,N-dimethylbenzenesulfonamide manufacturer3-Bromo-N,N-dimethylbenzenesulfonamide price3-Bromo-N,N-dimethylbenzenesulfonamide structure3-Bromo-N,N-dimethylbenzenesulfonamide SDSbuy 3-Bromo-N,N-dimethylbenzenesulfonamide3-Bromo-N,N-dimethylbenzenesulfonamide supplier3-Bromo-N,N-dimethylbenzenesulfonamide uses3-Bromo-N,N-dimethylbenzenesulfonamide molecular weightprice of 3-Bromo-N,N-dimethylbenzenesulfonamide3-Bromo-N,N-dimethylbenzenesulfonamide chemical name formula of 3-Bromo-N,N-dimethylbenzenesulfonamide

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

3-Bromo-N,N-dimethylbenzenesulfonamide

CAS No. 153435-80-4

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words