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(3AS,8aR)-2-(6-methylpyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole

  • CAS No. 1532531-18-2

  • Cat. No. CS-0512758
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(3AS,8aR)-2-(6-methylpyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole|CS-0512758

Structure of 1532531-18-2

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General Information

  • CAS No. 1532531-18-2
  • Cat. No. CS-0512758
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₄N₂O
  • Molecular Weight 250.30
  • Synonym(s) None
  • SMILES CC1=CC=CC(C2=N[C@]3([H])[C@](CC4=C3C=CC=C4)([H])O2)=N1

Description

This indeno[1,2-d]oxazole scaffold features a sterically defined 6-methylpyridin-2-yl moiety integrated at the 2-position, delivering enhanced electronic modulation and solubility. The fused bicyclic core provides rigidity and metabolic stability, enabling efficient incorporation into bioactive molecules.

Application

(3AS,8aR)-2-(6-Methylpyridin-2-yl)-3a,8a-dihydro-8H-indeno[1,2-d]oxazole serves as a versatile heterocyclic scaffold in medicinal chemistry, enabling efficient construction of complex polycyclic architectures. Its fused indeno-oxazole core exhibits excellent bench stability and compatibility with standard coupling reactions. The 6-methylpyridin-2-yl substituent provides a handle for further functionalization, while the rigid framework enhances conformational control in target molecule design.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   34.48
  • LogP   2.83282
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   1

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