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CS-W001157 4
Total: USD 88.00

1-Benzyl-7-azaindole

  • CAS No. 152955-68-5

  • Cat. No. CS-W001448
  • Purity≥98%
  • MDL No.MFCD09834870

*For research and further manufacturing use only, not for direct human use.

1-Benzyl-7-azaindole|CS-W001448

Structure of 152955-68-5

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General Information

  • CAS No. 152955-68-5
  • Cat. No. CS-W001448
  • Purity ≥98%
  • MDL No. MFCD09834870
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₁₂N₂
  • Molecular Weight 208.26
  • Synonym(s) 1-Benzylpyrrolo[2,3-b]pyridine
  • SMILES c1ccc(cc1)Cn1ccc2c1nccc2

Description

1-Benzyl-7-azaindole is a nitrogen-substituted heterocycle featuring a benzyl group at the 1-position and an azaindole core with enhanced electron density. This configuration improves solubility and stability in organic media, enabling efficient integration into pharmaceutical intermediates and functional materials. The compound serves as a key scaffold for bioactive molecule synthesis.

Application

1-Benzyl-7-azaindole serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to bioactive scaffolds through palladium-catalyzed cross-coupling and electrophilic functionalization. The benzyl group enhances solubility and stability during synthesis, while the 7-azaindole core provides strong hydrogen-bonding capability and favorable electronic properties for target-directed design. Its bench-stable nature and compatibility with common reaction conditions facilitate streamlined purification and integration into multi-step synthetic sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   17.82
  • LogP   3.0846
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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